| Ashley Irick | College of Health Professions | Audiology & Speech Pathology - Hearing & Speech Center | Associate Professor |
| Enrique Izaguirre | College of Medicine - Memphis | Radiation Oncology | Associate Professor |
| Franklin Ivers | College of Dentistry | Oral and Maxillofacial Surgery | Assistant Professor |
| Igor Iskusnykh | College of Medicine - Memphis | Anatomy & Neurobiology | Instructor |
| Jordan Isaac | College of Nursing | Acute and Tertiary Care | Assistant Professor |
| Matthew Ison | College of Medicine - Knoxville | Knox Anesthesiology | Assistant Professor |
| Nobuyuki Ikeda | College of Medicine - Memphis | Pediatrics - Peds Cardiology | Assistant Professor |
| Phillip Isaacman | College of Dentistry | General Dentistry | Assistant Professor |
| Rhys Irvine | College of Medicine - Knoxville | Knox Urology | Assistant Professor |
| Thomas Ireland | College of Medicine - Chattanooga | Chat Pediatrics | Assistant Professor |
| Tauheed Ishrat | College of Medicine - Memphis | Anatomy & Neurobiology | Associate Professor |
| Uzoma Ibebuogu | College of Medicine - Memphis | Medicine - Med Cardiology | Professor |
| Violiza Inoa Acosta | College of Medicine - Memphis | Neurology | Associate Professor |