| | Ashley Irick | College of Health Professions | Audiology & Speech Pathology - Hearing & Speech Center | Associate Professor |
| | Charlotte Isabel | College of Nursing | Community & Population Health | Assistant Professor |
| | Franklin Ivers | College of Dentistry | Oral and Maxillofacial Surgery | Assistant Professor |
| | Igor Iskusnykh | College of Medicine - Memphis | Anatomy & Neurobiology | Instructor |
| | Jordan Isaac | College of Nursing | Acute and Tertiary Care | Assistant Professor |
| | Matthew Ison | College of Medicine - Knoxville | Knox Anesthesiology | Assistant Professor |
| | Nobuyuki Ikeda | College of Medicine - Memphis | Pediatrics - Peds Cardiology | Assistant Professor |
| | Phillip Isaacman | College of Dentistry | General Dentistry | Assistant Professor |
| | Rhys Irvine | College of Medicine - Knoxville | Knox Urology | Assistant Professor |
| | Thomas Ireland | College of Medicine - Chattanooga | Chat Pediatrics | Assistant Professor |
| | Tauheed Ishrat | College of Medicine - Memphis | Anatomy & Neurobiology | Associate Professor |
| | Uzoma Ibebuogu | College of Medicine - Memphis | Medicine - Med Cardiology | Professor |
| | Violiza Inoa Acosta | College of Medicine - Memphis | Neurology | Associate Professor |